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GRC Collection (a selection from the Baltimore Longitudinal Study of Aging, BLSA)

Lifetime Study Gerontology Research Center Collection

This resource includes adult human skin fibroblast cultures from subjects participating in the Baltimore Longitudinal Study of Aging (BLSA). The BLSA was initiated to permit repeated observations of the same subjects over a long period of time to quantify true age changes and elucidate mechanisms underlying these changes. Observations documented include medical, genetic, biochemical, physiological, and behavioral variables. Information on the donor of any culture is available on request.

The cultures from these subjects form a unique resource for cellular aging research because of the extensive database of medical measurements on each donor, the wide range of donor ages (from 17-96), and the availability of an in vitro  lifespan measurement and karyotype for each culture.

Overview of the collection

Lifetime Study 
Individuals Sampled Multiple Times at Different Ages

Within the longitudinal study collection is a group of individuals for whom multiple fibroblast cultures are available. These individuals, 27 females and 93 males, were sampled at several times during their lifetime. The group includes 25 female subjects and 79 males subjects sampled at two different ages, 2 females and 12 males sampled at three different ages, and 2 males sampled at four different ages.

Individuals from 17-40 years of age


Gender		 Catalog ID and
Age at 1st Biopsy		 Catalog ID and
Age at 2nd Biopsy		 Catalog ID and
Age at 3rd Biopsy		 Catalog ID and
Age at 4th Biopsy
male AG06234  - 17 yr AG13153  - 30 yr    
male AG04054  - 29 yr AG11557  - 36 yr AG13442  - 46 yr  
male AG04441  - 29 yr AG13156  - 44 yr    
male AG05415  - 29 yr AG13353  - 45 yr    
male AG04151  - 30 yr AG13334  - 46 yr    
male AG04062  - 31 yr AG12660  - 46 yr    
male AG05412  - 31 yr AG13299  - 46 yr    
male AG08790  - 31 yr AG14245  - 48 yr    
female AG07471  - 32 yr AG12596  - 42 yr    
female AG07999  - 32 yr AG13066  - 42 yr    
male AG04150  - 32 yr AG14099  - 50 yr    
male AG06962  - 32 yr AG13244  - 44 yr    
female AG07472  - 33 yr AG12598  - 44 yr    
male AG05411  - 33 yr AG13285  - 48 yr    
female AG11796  - 35 yr AG13927  - 45 yr    
male AG04447  - 35 yr AG12602  - 50 yr    
male AG13105  - 35 yr AG13962  - 47 yr    
female AG05838  - 36 yr AG11745  - 43 yr    
female AG07308  - 36 yr AG14271  - 50 yr    
male AG08431  - 36 yr AG13337  - 51 yr    
male AG08049  - 37 yr AG12989  - 47 yr    
male AG08789  - 37 yr AG12361  - 50 yr    
male AG11799  - 37 yr AG13926  - 47 yr    
female AG09854  - 38 yr AG13781  - 47 yr    
male AG08818  - 38 yr AG13414  - 54 yr    
male AG04656  - 39 yr AG13075  - 54 yr    
female AG05245  - 40 yr AG13968  - 55 yr    
female AG07307  - 40 yr AG12493  - 50 yr    
male AG04462  - 40 yr AG11556  - 46 yr    

Individuals from 41-60 years of age


Gender		 Catalog ID and
Age at 1st Biopsy		 Catalog ID and
Age at 2nd Biopsy		 Catalog ID and
Age at 3rd Biopsy		 Catalog ID and
Age at 4th Biopsy
male AG08906  - 41 yr AG10942  - 50 yr AG12657  - 55 yr  
male AG04354  - 41 yr AG12733  - 56 yr    
male AG04654  - 41 yr AG07724  - 46 yr    
male AG06296  - 41 yr AG11365  - 47 yr    
male AG05416  - 42 yr AG11364  - 51 yr AG13145  - 57 yr  
male AG06307  - 42 yr AG10941  - 48 yr AG13067  - 53 yr  
male AG04145  - 42 yr AG11643  - 52 yr    
male AG04352  - 42 yr AG13367  - 58 yr    
male AG06235  - 42 yr AG13151  - 54 yr    
female AG08692  - 43 yr AG13150  - 52 yr    
male AG04556  - 43 yr AG13297  - 59 yr    
male AG06282  - 44 yr AG13292  - 56 yr    
male AG08904  - 45 yr AG10943  - 53 yr    
female AG08048  - 46 yr AG12988  - 56 yr    
male AG08792  - 46 yr AG12327  - 59 yr    
female AG05837  - 47 yr AG11248  - 53 yr    
female AG07118  - 47 yr AG13364  - 59 yr    
male AG04446  - 48 yr AG12851  - 63 yr    
male AG10049  - 48 yr AG16030  - 68 yr    
male AG05188  - 49 yr AG05805  - 52 yr AG13065  - 64 yr  
male AG04456  - 49 yr AG14251  - 68 yr    
male AG04655  - 49 yr AG12588  - 63 yr    
male AG06295  - 49 yr AG11013  - 55 yr    
female AG05270  - 50 yr AG12597  - 62 yr    
male AG09698  - 50 yr AG11645  - 54 yr    
male AG12956  - 50 yr AG16102  - 69 yr    
male AG07136  - 51 yr AG07144  - 53 yr    
male AG04453  - 52 yr AG10047  - 53 yr AG14048  - 71 yr  
male AG05186  - 52 yr AG11561  - 58 yr AG13369  - 68 yr  
male AG05103  - 52 yr AG12599  - 67 yr    
male AG08430  - 52 yr AG12964  - 66 yr    
female AG05275  - 53 yr AG13246  - 66 yr    
male AG04149  - 53 yr AG12965  - 68 yr    
male AG04439  - 53 yr AG12605  - 67 yr    
male AG05410  - 54 yr AG07723  - 58 yr AG13198  - 69 yr  
male AG09268  - 54 yr AG12850  - 68 yr    
male AG05192  - 55 yr AG09844  - 63 yr AG12587  - 69 yr  
female AG09162  - 55 yr AG12985  - 63 yr    
male AG06287  - 55 yr AG13018  - 67 yr    
female AG07714  - 56 yr AG12927  - 66 yr    
male AG06305  - 56 yr AG13245  - 68 yr    
female AG05844  - 57 yr AG11362  - 63 yr AG13144  - 69 yr  
male AG04146  - 57 yr AG07123  - 62 yr    
male AG04458  - 57 yr AG09158  - 59 yr    
male AG07997  - 58 yr AG13197  - 69 yr    
male AG04353  - 59 yr AG05804  - 63 yr    
male AG04380  - 59 yr AG13348  - 75 yr    
female AG07310  - 60 yr AG13358  - 72 yr    
male AG06288  - 60 yr AG10944  - 66 yr    
male AG10883  - 60 yr AG16359  - 79 yr    

Individuals from 61-80 years of age


Gender		 Catalog ID and
Age at 1st Biopsy		 Catalog ID and
Age at 2nd Biopsy		 Catalog ID and
Age at 3rd Biopsy		 Catalog ID and
Age at 4th Biopsy
female AG09878  - 61 yr AG12589  - 68 yr    
male AG04350  - 62 yr AG11555  - 69 yr    
male AG05417  - 63 yr AG11746  - 72 yr    
male AG06881  - 63 yr AG11247  - 69 yr    
male AG09157  - 63 yr AG13333  - 78 yr    
male AG04552  - 64 yr AG13152  - 80 yr    
male AG09160  - 64 yr AG11358  - 71 yr    
male AG12939  - 64 yr AG13223  - 73 yr    
female AG05266  - 65 yr AG11161  - 73 yr    
male AG04551  - 65 yr AG09270  - 67 yr AG11019  - 74 yr  
male AG04659  - 65 yr AG05283  - 69 yr AG11243  - 74 yr  
male AG06294  - 65 yr AG09697  - 67 yr AG13084  - 76 yr  
male AG04454  - 66 yr AG13076  - 82 yr    
male AG04461  - 66 yr AG13345  - 82 yr    
male AG06959  - 67 yr AG13329  - 79 yr    
male AG06957  - 68 yr AG13146  - 80 yr    
male AG12955  - 68 yr AG14036  - 84 yr    
male AG13004  - 68 yr AG13975  - 81 yr    
male AG05099  - 69 yr AG09269  - 72 yr    
male AG06236  - 69 yr AG11014  - 76 yr    
male AG07801  - 70 yr AG05271  - 73 yr AG11157  - 80 yr AG13349  - 86 yr
female AG07309  - 70 yr AG13300  - 81 yr    
female AG07479  - 70 yr AG11018  - 75 yr    
male AG06284  - 70 yr AG13308  - 75 yr    
male AG11724  - 70 yr AG11727  - 71 yr    
male AG13097  - 70 yr AG14421  - 83 yr    
male AG06242  - 71 yr AG11648  - 78 yr    
male AG06879  - 71 yr AG12443  - 82 yr    
male AG04455  - 72 yr AG05414  - 73 yr    
female AG06952  - 73 yr AG11020  - 79 yr AG13077  - 85 yr
female AG07122  - 73 yr AG11081  - 78 yr    
male AG04459  - 73 yr AG11693  - 75 yr    
male AG05096  - 73 yr AG13129  - 89 yr    
male AG11073  - 75 yr AG13993  - 83 yr    
male AG04144  - 76 yr AG09558  - 85 yr    
female AG09879  - 77 yr AG12322  - 83 yr    
male AG07135  - 77 yr AG07143  - 80 yr AG11488  - 84 yr AG12788  - 90 yr

Individuals from 81-96 years of age


Gender		 Catalog ID and
Age at 1st Biopsy		 Catalog ID and
Age at 2nd Biopsy		 Catalog ID and
Age at 3rd Biopsy		 Catalog ID and
Age at 4th Biopsy
male AG04057  - 81 yr AG11730  - 84 yr    
male AG04382  - 81 yr AG08791  - 84 yr    
male AG04457  - 83 yr AG05248  - 87 yr    
male AG05274  - 84 yr AG10884  - 87 yr    
female AG05247  - 87 yr AG09602  - 92 yr    
male AG06308  - 89 yr AG07725  - 91 yr    
male AG04064  - 92 yr AG08433  - 94 yr