Title: Screens in aging-relevant human ALS-motor neurons identify MAP4Ks as therapeutic targets for the disease
Samples Used: AG05811, AG08517, AG09969, AG11733, AG12989
Title: Culicoides-Specific Fitness Increase of Vesicular Stomatitis Virus in Insect-to-Insect Infections
Samples Used: AG08113
Title: Distinct Effects of Aducanumab and Lecanemab on Intraneuronal Endogenous Aβ42 and Phosphorylated Tau in Alzheimer's Disease Treatment
Samples Used: AG08517, AG06848
Title: Pharmacologic Ascorbate Radiosensitizes Pancreatic Cancer but Radioprotects Normal Tissue: The Role of Oxidative Stress-Induced Lipid Peroxidation
Samples Used:
Title: Increased PTCHD4 expression via m6A modification of PTCHD4 mRNA promotes senescent cell survival
Samples Used: AG06814
Title: Age-dependent alterations in the human striatum identify a PPP1R15B-miR-196a node as a modier of Huntington’s disease phenotypes
Samples Used: AG13369, AG08379, AG06858
Title: Cell growth and mitochondrial anomalies in induced pluripotent stem cells with Presenilin 1 mutation
Samples Used: AG04152, AG09602, AG08509, GM1706, AG04159, AG06840, AG06840, AG08541, AG08597, AG08563
Title: Quercetin induces senolysis of doxorubicin-induced senescent fibroblasts by reducing autophagy, preventing their pro-tumour effect on osteosarcoma cells
Samples Used: AG06814
Title: Cardiac and skeletal muscle manifestations in the G608G mouse model of Hutchinson-Gilford progeria syndrome
Samples Used: AG06299, AG06917
Title: Ascites microenvironment conditions the peritoneal pre-metastatic niche to promote the implantation of ovarian tumor spheroids: Involvement of fibrinogen/fibrin and αV and α5β1 integrins
Samples Used: AG07086
Title: Identification of senescent cell subpopulations by CITE-seq analysis
Samples Used: AG06814
Title: Vesicular Stomatitis Virus Elicits Early Transcriptome Response in Culicoides sonorensis Cells
Samples Used: AG08113
Title: UGDH promotes tumor-initiating cells and a fibroinflammatory tumor microenvironment in ovarian cancer
Samples Used: AG07090
Title: α-Synuclein-dependent increases in PIP5K1γ drive inositol signaling to promote neurotoxicity
Samples Used: AG20445
Title: The Apolipoprotein E neutralizing antibody inhibits SARS-CoV-2 infection by blocking cellular entry of lipoviral particles
Samples Used: AG14048, AG06869
Title: Evaluation of potential reference genes in the biting midge Culicoides sonorensis for real-time quantitative PCR analyses
Samples Used: AG08113
Title: PTBP2 attenuation facilitates fibroblast to neuron conversion by promoting alternative splicing of neuronal genes
Samples Used: AG22056, AG04451, AG16146, AG04452, AG02603
Title: Typhoid toxin hijacks Wnt5a to establish host senescence and Salmonella infection
Samples Used: I90
Title: The YAP-TEAD complex promotes senescent cell survival by lowering endoplasmic reticulum stress
Samples Used: AG07086
Title: BACE1 and SCD1 are associated with neurodegeneration
Samples Used: AG13145, AG11482, AG14284, AG12786
Title: A loss-of-function mutation in human Oxidation Resistance 1 disrupts the spatial-temporal regulation of histone arginine methylation in neurodevelopment
Samples Used: AG05836
Title: ApoE4-dependent lysosomal cholesterol accumulation impairs mitochondrial homeostasis and oxidative phosphorylation in human astrocytes
Samples Used: AG10788
Title: Senescence, regulators of alternative splicing and effects of trametinib treatment in progeroid syndromes
Samples Used: AG06917, AG05233
Title: Developing a human iPSC-derived three-dimensional myelin spheroid platform for modeling myelin diseases
Samples Used: I90
Title: BACE1 and SCD1 are associated with neurodegeneration
Samples Used: AG07086
Title: Controlled and customizable baculovirus NOS3 gene delivery using PVA-based hydrogel systems
Samples Used: AG14133
Title: Synthesis, cytotoxic activity evaluation and mechanistic investigation of novel 3,7-diarylsubstituted 6-azaindoles
Samples Used: AG01523
Title: BACE1 and SCD1 are associated with neurodegeneration
Samples Used: Unspecified
Title: Correlating cryo-super resolution radial fluctuations and dual-axis cryo-scanning transmission electron tomography to bridge the light-electron resolution gap
Samples Used: AG06814
Title: Scalable production of tissue-like vascularized liver organoids from human PSCs
Samples Used: AG05836
Title: A novel molecular class that recruits HDAC/MECP2 complexes to PU.1 motifs reduces neuroinflammation
Samples Used: AG09173
Title: Enhanced cell viscosity: A new phenotype associated with lamin A/C alterations
Samples Used: AG06795, AG06917
Title: Development of a three-dimensional organoid model to explore early retinal phenotypes associated with Alzheimer's disease
Samples Used: AG25367, AG25370
Title: Human iPS cell-derived sensory neurons can be infected by SARS-CoV-2
Samples Used: AG07095
Title: Thoracic adipose tissue contributes to severe virus infection of the lung
Samples Used: I90
Title: Mass Cytometry as a Tool for Investigating Senescence in Multiple Model Systems
Samples Used: AG06814
Title: Supercritical millifluidic process for siRNA encapsulation in nanoliposomes for potential Progeria treatment (ex-vivo assays)
Samples Used: AG07095
Title: Influence of the Hypersensitivity to Low Dose Phenomenon on the Tumor Response to Hypofractionated Stereotactic Body Radiation Therapy
Samples Used: AG01521
Title: Influenza Virus-Induced Paracrine Cellular Senescence of the Lung Contributes to Enhanced Viral Load
Samples Used: I90
Title: FGFR-mediated ERK1/2 signaling contributes to mesendoderm and definitive endoderm formation in vitro
Samples Used: AG22719
Title: Biological Activities of Ceratonia siliqua Pod and Seed Extracts: A Comparative Analysis of Two Cretan Cultivars
Samples Used: AG01523
Title: Lysosomal dysfunction in Down syndrome and Alzheimer mouse models is caused by v-ATPase inhibition by Tyr682-phosphorylated APP βCTF
Samples Used: AG06922, AG07095, AG07096
Title: Autophagy Inhibition via Hydroxychloroquine or 3-Methyladenine Enhances Chemotherapy-Induced Apoptosis in Neuro-Blastoma and Glioblastoma
Samples Used: AG09309
Title: Early chromosome condensation by XIST builds A-repeat RNA density that facilitates gene silencing
Samples Used: AG06173
Title: Astrocytic response mediated by the CLU risk allele inhibits OPC proliferation and myelination in a human iPSC model
Samples Used: AG14048, AG06869
Title: Third-Generation Single-Molecule Sequencing for Preimplantation Genetic Testing of Aneuploidy and Segmental Imbalances
Samples Used: AG17487
Title: Biallelic variants in CRIPT cause a Rothmund-Thomson-like syndrome with increased cellular senescence
Samples Used: AG05013, AG18371, AG17524
Title: Chemically induced reprogramming to reverse cellular aging
Samples Used: AG08433, AG11498, AG27602
Title: An engineered T-cell engager with selectivity for high mesothelin-expressing cells and activity in the presence of soluble mesothelin
Samples Used: AG07086
Title: Empagliflozin reduces endoplasmic reticulum stress associated TXNIP/NLRP3 activation in tunicamycin-stimulated aortic endothelial cells
Samples Used: AG09799
Title: Nicotinamide N-methyltransferase Mediates Lipofibroblast-Myofibroblast Transition and Apoptosis Resistance
Samples Used: I90
Title: FGFR-mediated ERK1/2 signaling contributes to mesendoderm and definitive endoderm formation in vitro
Samples Used: AG16102
Title: Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models
Samples Used: AG05311
Title: Deciphering Stromal Changes between Metastatic and Non-metastatic Canine Mammary Carcinomas
Samples Used: AG06173
Title: A recurrent homozygous LMNA missense variant p.Thr528Met causes atypical progeroid syndrome characterized by mandibuloacral dysostosis, severe muscular dystrophy, and skeletal deformities
Samples Used: AG08498
Title: Toward an Early Diagnosis for Alzheimer’s Disease Based on the Perinuclear Localization of the ATM Protein
Samples Used: AG17524, AG01972, AG06300, AG11415, AG21158, AG06840, AG06844, AG06848, AG06869, AG07376, AG08170, AG08541, AG09908
Title: Machine learning approaches based on fibroblast morphometry do not predict ALS
Samples Used: AG13244, AG12598, AG13285, AG14284, AG11482, AG13150, AG13968, AG12657, AG12597, AG12851, AG11489, AG12964, AG12850, AG13144, AG13994, AG14048, AG13348, AG13990
Title: Single-Molecule Telomere Assay via Optical Mapping (SMTA-OM) Can Potentially Define the ALT Positivity of Cancer
Samples Used: I90
Title: DPP4 inhibition impairs senohemostasis to improve plaque stability in atherosclerotic mice
Samples Used: AG06814
Title: Cellular allostatic load is linked to increased energy expenditure and accelerated biological aging
Samples Used: AG01439
Title: A simple, flexible, and high-efficiency western blot analysis for age-related human induced neurons
Samples Used: AG08517
Title: In search for mitochondrial biomarkers of Parkinson's disease: Findings in parkin-mutant human fibroblasts
Samples Used: AG14285, AG13145, AG06010
Title: Pooled analysis of frontal lobe transcriptomic data identifies key mitophagy gene changes in Alzheimer's disease brain
Samples Used: AG02261, AG16086, AG07377, AG06263
Title: Three induced pluripotent stem cell lines (TRNDi033-A, TRNDi034-A, TRNDi035-A) generated from lymphoblasts of three apparently healthy individuals
Samples Used: AG14724, AG20473
Title: SERCA2 phosphorylation at serine 663 is a key regulator of Ca2+ homeostasis in heart diseases
Samples Used: AG08498
Title: Oxidation of Hydrogen Sulfide to Polysulfide and Thiosulfate by a Carbon Nanozyme: Therapeutic Implications with an Emphasis on Down Syndrome
Samples Used: AG10317, AG09802, AG09394
Title: Developing Hypoimmunogenic Human iPSC-Derived Oligodendrocyte Progenitor Cells as an Off-The-Shelf Cell Therapy for Myelin Disorders
Samples Used: I90
Title: The spontaneous immortalization probability of mammalian cell culture strains, as their proliferative capacity, correlates with species body mass, not longevity
Samples Used: AG07107, AG06252, AG07127, AG05251, AG08029, AG07906, AG08032, AG10466
Title: Activation of endoplasmic reticulum stress in premature aging via the inner nuclear membrane protein SUN2
Samples Used: AG08470, AG08466
Title: Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models
Samples Used: AG05811, AG11725, AG08712
Title: Heat shock proteins and cellular senescence in humans: A systematic review
Samples Used: I90
Title: Immediate effects of acute Mars mission equivalent doses of SEP and GCR radiation on the murine gastrointestinal system-protective effects of curcumin-loaded nanolipoprotein particles (cNLPs)
Samples Used: AG05965
Title: 3D ECM-Based Scaffolds Boost Young Cell Secretome-Derived EV Rejuvenating Effects in Senescent Cells
Samples Used: AG09602
Title: The E3 Ubiquitin Ligase TRIM21 Regulates Basal Levels of PDGFRβ
Samples Used: AG01523
Title: Age-Related Fourier-Transform Infrared Spectroscopic Changes in Protein Conformation in an Aging Model of Human Dermal Fibroblasts
Samples Used: AG22153, AG10803, AG02222, AG16102
Title: Pleiotropic effects of BAFF on the senescence-associated secretome and growth arrest
Samples Used: AG06814, I-90
Title: Tau pathology epigenetically remodels the neuron-glial cross-talk in Alzheimer's disease
Samples Used: AG11414, AG11368, AG08525, AG08509
Title: 4-Methylumbelliferone-Functionalized Polyphosphazene and Its Assembly into Biocompatible Fluorinated Nanocoatings with Selective Antiproliferative Activity
Samples Used: AG01519
Title: Matrix Metalloproteinases Contribute to the Calcification Phenotype in Pseudoxanthoma Elasticum
Samples Used: AG12786, AG13145, AG11482, AG14284, AG06307
Title: Ageing-associated changes in transcriptional elongation influence longevity
Samples Used: I90
Title: Deregulation of ER-mitochondria contact formation and mitochondrial calcium homeostasis mediated by VDAC in fragile X syndrome
Samples Used: AG01552
Title: Requirement of transcription-coupled nucleotide excision repair for the removal of a specific type of oxidatively induced DNA damage
Samples Used: AG10076
Title: Assessment of neurotransmitter release in human iPSC-derived neuronal/glial cells: a missing in vitro assay for regulatory developmental neurotoxicity testing
Samples Used: I-90
Title: Senescence Induced by UVB in Keratinocytes Impairs Amino Acids Balance
Samples Used: AG06814
Title: Transcriptional activation of endogenous Oct4 via the CRISPR/dCas9 activator ameliorates Hutchinson-Gilford progeria syndrome in mice
Samples Used: AG11498
Title: The Consideration of Pseudoxanthoma Elasticum as a Progeria Syndrome
Samples Used: AG13145, AG11482, AG14284
Title: Cell Attachment and Laminin Immobilization on Hydrogels Coated by Plasma Deposited Nitrogen, Oxygen or Sulfur Based Organic Thin Films
Samples Used: AG04677
Title: Machine learning dissection of human accelerated regions in primate neurodevelopment
Samples Used: AG07095
Title: The evolution of the human DNA replication timing program
Samples Used: AG25370, NG03259, NG03344, NG03506, NG04103, NG05140, NG07091, NG07896, NG08006, NG17485, NG17487, NG20427, NG20429, NG20606, NG20607, NG20623, NG20625, NG20626, NG20627
Title: Ginsenoside Rb2 suppresses cellular senescence of human dermal fibroblasts by inducing autophagy
Samples Used: AG08498
Title: Accurate Detection and Frequency of Abnormal Ploidy in the Human Blastocyst
Samples Used: AG05025
Title: A cell-penetrant peptide blocking C9ORF72-repeat RNA nuclear export reduces the neurotoxic effects of dipeptide repeat proteins
Samples Used: AG08620
Title: Model of collective detachment in high-grade serous ovarian cancer demonstrates that tumor spheroids produce ECM to support metastatic processes
Samples Used: AG07086
Title: Telomere-to-mitochondria signalling by ZBP1 mediates replicative crisis
Samples Used: I-90, AG06814
Title: Small-molecule Polθ inhibitors provide safe and effective tumor radiosensitization in preclinical models
Samples Used: AG01552
Title: Directed differentiation of human iPSCs to functional ovarian granulosa-like cells via transcription factor overexpression
Samples Used: AG07141
Title: Identification of a derivative of the alkaloid emetine as an inhibitor of the YAP-TEAD interaction and its potential as an anticancer agent
Samples Used: AG07086
Title: Systematic estimation of biological age of in vitro cell culture systems by an age-associated marker panel
Samples Used: AG07095, AG09602, AG04059, AG03141, AG06300
Title: The human inactive X chromosome modulates expression of the active X chromosome
Samples Used: AG09389, AG10317, AG09393, AG17485, AG13455, AG14947, AG16945, AG08006, AG14724, AG15033, AG09802, AG14953, AG15782, AG15060, AG15013, AG08606, AG10316, AG14988
Title: Hyaluronan-Induced CD44-iASPP Interaction Affects Fibroblast Migration and Survival
Samples Used: AG01523
Title: Selective ablation of primary and paracrine senescent cells by targeting iron dyshomeostasis
Samples Used: AG09872, AG10774, AG10770
Title: Fabrication of antibacterial and biocompatible 3D printed Manuka-Gelatin based patch for wound healing applications
Samples Used: AG09319, AG22720
Title: Unique progerin C-terminal peptide ameliorates Hutchinson–Gilford progeria syndrome phenotype by rescuing BUBR1
Samples Used: AG09602
Title: Regulation of Mesenchymal Cell Fate by Transfer of Active Gasdermin-D via Monocyte-Derived Extracellular Vesicles
Samples Used: I90-10
Title: Multi-omic integration reveals cell-type-specific regulatory networks of insulin resistance in distinct ancestry populations
Samples Used: AG17928, AG17929
Title: Neuroprotective Effects of Licochalcone D in Oxidative-Stress-Induced Primitive Neural Stem Cells from Parkinson's Disease Patient-Derived iPSCs
Samples Used: AG02261
Title: Intraperitoneal administration of cabazitaxel-loaded nanoparticles in peritoneal metastasis models
Samples Used: AG07086
Title: Rescue of Mitochondrial Function in Hutchinson-Gilford Progeria Syndrome by the Pharmacological Modulation of Exportin CRM1
Samples Used: AG08469, AG11513, AG11498
Title: Anti-hsa-miR-59 alleviates premature senescence associated with Hutchinson-Gilford progeria syndrome in mice
Samples Used: AG05247, AG09602
Title: Characterization of cellular phenotypes in neurons derived from induced pluripotent stem cells of male patients with Fabry disease
Samples Used: AG08498
Title: Identification of marker genes to monitor residual iPSCs in iPSC-derived products
Samples Used: AG09429
Title: Deubiquitinase USP2 stabilizes the MRE11-RAD50-NBS1 complex at DNA double-strand break sites by counteracting the ubiquitination of NBS1
Samples Used: AG17524, AG18371
Title: Low dose hyper-radiosensitivity in normal human cells
Samples Used: AG01522
Title: Transcriptional profiling of Hutchinson-Gilford Progeria syndrome fibroblasts reveals deficits in mesenchymal stem cell commitment to differentiation related to early events in endochondral ossification
Samples Used: AG01178, AG03198, AG06917, AG07493, AG08466, AG10578, AG10677, AG11572, AG11513, AG11513, AG03257
Title: Nuclear envelope morphology change upon repetitive treatment with modified antisense oligonucleotides targeting Hutchinson-Gilford Progeria Syndrome
Samples Used: AG03513
Title: Rapid emergence of transcriptional heterogeneity upon molecular stress predisposes cells to two distinct states of senescence
Samples Used: I90
Title: Oxidative Damage Induced Telomere Mediated Genomic Instability in Cells from Ataxia Telangiectasia Patients
Samples Used: AG04405, AG03059
Title: A Polymeric Nanoparticle Formulation for Targeted mRNA Delivery to Fibroblasts
Samples Used: AG08468
Title: Protocol to image and quantify nucleocytoplasmic transport in cultured cells using fluorescent in situ hybridization and a dual reporter system
Samples Used: AG07473
Title: An open access, machine learning pipeline for high-throughput quantification of cell morphology
Samples Used: I90
Title: The metastatic capacity of high-grade serous ovarian cancer cells changes along disease progression: inhibition by mifepristone
Samples Used: AG06814
Title: Protein mishandling and impaired lysosomal proteolysis generated through calcium dysregulation in Alzheimer's disease
Samples Used:
Title: Zinc controls PML nuclear body formation through regulation of a paralog specific auto-inhibition in SUMO1
Samples Used:
Title: miR-4734 conditionally suppresses ER stress-associated proinflammatory responses
Samples Used: AG14608
Title: Alginate Microsphere Encapsulation of Drug-Loaded Nanoparticles: A Novel Strategy for Intraperitoneal Drug Delivery
Samples Used: AG07086
Title: Suppressing gain-of-function proteins via CRISPR/Cas9 system in SCA1 cells
Samples Used: AG21802, AG21754, AG21805
Title: New human ATM variants are able to regain ATM functions in ataxia telangiectasia disease
Samples Used: AG09429
Title: The Heterochromatin protein 1 is a regulator in RNA splicing precision deficient in ulcerative colitis
Samples Used:
Title: Impact of the redox environment on propagation of radiation bystander effects: The modulating effect of oxidative metabolism and oxygen partial pressure
Samples Used: AG01522
Title: Inflammation as a chemoprevention target in asbestos-induced malignant mesothelioma
Samples Used: AG07086
Title: ATRX modulates the escape from a telomere crisis
Samples Used: AG05965
Title: Oxidative Stress Kinase Activation and Impaired Insulin Receptor Signaling Precede Overt Alzheimer's Disease Neuropathology
Samples Used: AG25367, AG27606
Title: Cell division drives DNA methylation loss in late-replicating domains in primary human cells
Samples Used: AG06561, AG21859, AG21839, AG21837, AG11182, AG11546, AG16146
Title: Morphometric imaging biomarker identifies Alzheimer's disease even among mixed dementia patients
Samples Used: AG05770, AG08245, AG08527, AG06840, AG04159, AG06844, AG10788, AG06869, AG11368, AG05810, AG08395, AG06274, AG09977, AG11730, AG12927, AG12998, AG04146, AG07123, AG13358, AG04461, AG07714, AG12438, AG05840
Title: Analysis of Primary Cilium Expression and Hedgehog Pathway Activation in Mesothelioma Throws Back Its Complex Biology
Samples Used: AG07086
Title: Age-related Huntington’s disease progression modeled in directly reprogrammed patient-derived striatal neurons highlights impaired autophagy
Samples Used: AG04453, AG10047, AG12956, AG08379, AG11798
Title: Transient inhibition of p53 enhances prime editing and cytosine base-editing efficiencies in human pluripotent stem cells
Samples Used: AG01972
Title: APOE ε4-dependent effects on the early amyloid pathology in induced neurons of patients with Alzheimer’s disease
Samples Used: AG06848, AG09908, AG05810, AG05770
Title: Excessive negative regulation of type I interferon disrupts viral control in individuals with Down syndrome
Samples Used: AG08942
Title: Long-range phasing of dynamic, tissue-specific and allele-specific regulatory elements
Samples Used: AG04450
Title: Agent-Based Modeling Predicts Rac1 Is Critical For Ovarian Cancer Metastasis
Samples Used: AG07086
Title: Lamin A/C impairments cause mitochondrial dysfunction by attenuating PGC1α and the NAMPT-NAD+ pathway
Samples Used: AG03258, AG03198, AG03512, AG03513, AG06299, AG06917
Title: SerpinE1 drives a cell-autonomous pathogenic signaling in Hutchinson–Gilford progeria syndrome
Samples Used: AG11513, AG07095
Title: Assuring the Biofunctionalization of Silicone Covalently Bonded to Rhamnolipids: Antibiofilm Activity and Biocompatibility
Samples Used: AG22719
Title: The function of FUS in neurodevelopment revealed by the brain and spinal cord organoids
Samples Used: AG07121
Title: Nuclear morphology is a deep learning biomarker of cellular senescence
Samples Used: AG08498
Title: The lysosomal proteome of senescent cells contributes to the senescence secretome
Samples Used: I90
Title: LINE-1 RNA causes heterochromatin erosion and is a target for amelioration of senescent phenotypes in progeroid syndromes
Samples Used: AG06234, AG10108, AG09309, AG10803, AG03257, AG06917, AG11498, AG10578, AG11572, AG06297, AG041100, AG00989, AG00990, AG09233, AG12798, AG24467, AG06300, AG00780, AG05229
Title: Zinc controls PML nuclear body formation through regulation of a paralog specific auto-inhibition in SUMO1
Samples Used: I90
Title: Activation of the JNKs/ATM-p53 axis is indispensable for the cytoprotection of dermal fibroblasts exposed to UVB radiation
Samples Used: AG01523
Title: Role of the cystathionine β-synthase / H2S pathway in the development of cellular metabolic dysfunction and pseudohypoxia in down syndrome
Samples Used: AG07096 AG05397
Title: APOE4-carrying human astrocytes oversupply cholesterol to promote neuronal lipid raft expansion and Aβ generation
Samples Used: AG09173
Title: Bonding antimicrobial rhamnolipids onto medical grade PDMS: A strategy to overcome multispecies vascular catheter-related infections
Samples Used: AG22719
Title: N-oleoylethanolamide treatment of lymphoblasts deficient in Tafazzin improves cell growth and mitochondrial morphology and dynamics
Samples Used: AG15022 AG14731 AG14948 AG14750 AG14947
Title: Comparison of Endemic and Epidemic Vesicular Stomatitis Virus Lineages in Culicoides sonorensis Midges
Samples Used: AG08113
Title: miR-376a-3p and miR-376b-3p overexpression in Hutchinson-Gilford progeria fibroblasts inhibits cell proliferation and induces premature senescence
Samples Used: AG11513 AG11498 AG08498 AG07095 AG08471
Title: MPTAC links alkylation damage signaling to sterol biosynthesis
Samples Used: AG14953
Title: Detection of Pathological Markers of Neurodegenerative Diseases following Microfluidic Direct Conversion of Patient Fibroblasts into Neurons
Samples Used: AG11732 AG04062 AG04060 AG04148 AG07141 AG07801 AG09602 AG08711 AG06848 AG06840 AG20442 AG20446 AG20443 AG08395
Title: ATase inhibition rescues age-associated proteotoxicity of the secretory pathway
Title: Salt-Inducible Kinase 1 is a potential therapeutic target in Desmoplastic Small Round Cell Tumor
Samples Used: AG07086
Title: Compound screen identifies the small molecule Q34 as an inhibitor of SARS-CoV-2 infection
Samples Used: AG06869
Title: Combination of Melatonin and Small Molecules Improved Reprogramming Neural Cell Fates via Autophagy Activation
Samples Used: AG08379 AG09019
Title: New bioactive 5-arylcarboximidamidopyrazolo[3,4-c]pyridines: Synthesis, cytotoxic activity, mechanistic investigation and structure-activity relationships
Samples Used: AG01523
Title: STING regulates peripheral nerve regeneration and colony stimulating factor 1 receptor (CSF1R) processing in microglia
Samples Used: AG09429
Title: The multicellular signalling network of ovarian cancer metastases
Samples Used: AG07086
Title: Inactivity of peptidase ClpP causes primary accumulation of mitochondrial disaggregase ClpX with its interactors at the nucleoid and RNA granule
Samples Used: AG06103 AG02261 AG06858
Title: Ultraviolet Radiation Protection Potentials of Methylene Blue for Human Skin and Coral Reef Health
Samples Used: AG09266 AG11695 AG08434 AG11725
Title: Down-syndrome-induced senescence disrupts the nuclear architecture of neural progenitors
Samples Used: AG05397 AG06922
Title: Accumulation of APP-CTF induces mitophagy dysfunction in the iNSCs model of Alzheimer’s disease
Samples Used: AG09035
Title: Novel patient-derived models of desmoplastic small round cell tumor confirm a targetable dependency on ERBB signaling
Samples Used: AG07086
Title: Human pluripotent stem cell-derived functional sympathetic neurons express ACE2 and RAAS components: a framework for studying the effect of COVID-19 on sympathetic responsiveness
Samples Used: AG02602
Title: Endotype reversal as a novel strategy for screening drugs targeting familial Alzheimer’s disease
Samples Used: AG06840
Title: A Rare Mutation in LMNB2 Associated with Lipodystrophy Drives Premature Cell Senescence
Samples Used: AG09309
Title: In vivo base editing rescues Hutchinson–Gilford progeria syndrome in mice
Samples Used: AG03257
Title: Systematic screening identifies therapeutic antisense oligonucleotides for Hutchinson–Gilford progeria syndrome
Samples Used: AG06297
Title: Trisomy 21 impairs PGE2 production in dermal fibroblasts
Samples Used: AG07438 AG05024 AG07095 AG06922 AG10803 AG08942 AG06103
Title: Nuclear Transport Factor 2 (NTF2) suppresses WM983B metastatic melanoma by modifying cell migration, metastasis, and gene expression
Samples Used: AG21857
Title: Non-human primate adenoviruses of the Human Adenovirus B species are potent and broadly-acting oncolytic vector candidates
Samples Used: AG05965
Title: Novel patient-derived models of DSRCT enable validation of ERBB signaling as a potential therapeutic vulnerability
Samples Used: AG07086
Title: Genome-wide screening in human kidney organoids identifies developmental and disease-related aspects of nephrogenesis
Samples Used: AG09429
Title: Non-invasive prenatal screening for foetal trisomy: An assessment of reliability and reporting
Samples Used: AG09387 AG09394
Title: Cellular Senescence limits Translational Readthrough
Samples Used: I90
Title: Acquired Radioresistance in Cancer Associated Fibroblasts is Concomitant with Enhanced Antioxidant Potential and DNA Repair Capacity
Samples Used: AG01522
Title: Investigating spatial fractionation and radiation induced bystander effects: a mathematical modelling approach
Samples Used: AG01522
Title: Generation of gene edited hiPSC from familial Alzheimer's disease patient carrying N141I missense mutation in presenilin 2
Samples Used: AG09908
Title: Modeling Sporadic Alzheimer’s Disease in Human Brain Organoids under Serum Exposure
Samples Used: AG06869, AG14048, and AG10884
Title: Cellular junction and mesenchymal factors delineate an endometriosis-specific response of endometrial stromal cells to the mesothelium
Samples Used: AG07086
Title: High concordance in preimplantation genetic testing for aneuploidy between automatic identification via Ion S5 and manual identification via Miseq
Samples Used: AG12070
Title: N-Acetylcysteine prevents amyloid-β secretion in neurons derived from human pluripotent stem cells with trisomy 21
Samples Used: AG06892
Title: Stable maintenance of the Mre11-Rad50-Nbs1 complex is sufficient to restore the DNA double-strand break response in cells lacking RecQL4 helicase activity
Samples Used: AG09173
Title: APOE4-carrying human astrocytes oversupply cholesterol to promote neuronal lipid raft expansion and Aβ generation
Samples Used: AG09173
Title: ZNF768 links oncogenic RAS to cellular senescence
Samples Used: I90-10
Title: Off-the-shelf proximity biotinylation for interaction proteomics
Samples Used: AG08469
Title: Generation of inducible pluripotent stem cell lines from Alzheimer’s disease patients with APOE e3/e3 genotype
Samples Used: AG10039 and AG08242
Title: CD147 mediates the CD44s-dependent differentiation of myofibroblasts driven by transforming growth factor-β1
Samples Used: AG02262
Title: Novel method of real-time PCR-based screening for common fetal trisomies
Samples Used: AG05121, AG11552, AG07167, AG0801, and AG12070
Title: Genotoxic stress in constitutive trisomies induces autophagy and the innate immune response via the cGAS-STING pathway
Samples Used: AG04392 and AG21708
Title: Impacts of Infectious Dose, Feeding Behavior, and Age of Culicoides sonorensis Biting Midges on Infection Dynamics of Vesicular Stomatitis Virus
Samples Used: AG08113
Title: NF-κB/IKK activation by small extracellular vesicles within the SASP
Samples Used: AG16086, AG06240, AG13152, and AG13222
Title: Progerin impairs 3D genome organization and induces fragile telomeres by limiting the dNTP pools
Samples Used: AG06297, AG11498, and AG11513
Title: BING, a novel antimicrobial peptide isolated from Japanese medaka plasma, targets bacterial envelope stress response by suppressing cpxR expression
Samples Used: AG06858
Title: A deep learning approach to identify gene targets of a therapeutic for human splicing disorders
Samples Used: AG16409
Title: Co-development of central and peripheral neurons with trunk mesendoderm in human elongating multi-lineage organized gastruloids
Samples Used: AG08498
Title: FOXM1 repression increases mitotic death upon antimitotic chemotherapy through BMF upregulation
Samples Used: AG10884
Title: Generation of six human iPSC lines from patients with a familial Alzheimer’s disease (n = 3) and sex- and age-matched healthy controls (n = 3)
Samples Used: AG06840, AG06848, and AG09908
Title: The nucleoplasmic interactions among Lamin A/C-pRB-LAP2α-E2F1 are modulated by dexamethasone
Samples Used: AG09429
Title: Human WRN is an intrinsic inhibitor of progerin, abnormal splicing product of lamin A
Samples Used: AG09603 and AG05229
Title: Macrophage Plasticity and Function in the Lung Tumour Microenvironment Revealed in 3D Heterotypic Spheroid and Explant Models
Samples Used: AG02603
Title: G-quadruplexes originating from evolutionary conserved L1 elements interfere with neuronal gene expression in Alzheimer’s disease
Samples Used: AG04152, AG09602, AG08243, and AG08259
Title: Statins as a Therapeutic Approach for the Treatment of Pseudoxanthoma Elasticum Patients: Evaluation of the Spectrum Efficacy of Atorvastatin In Vitro
Samples Used: AG13145, AG11482, and AG14284
Title: Mitovesicles are a novel population of extracellular vesicles of mitochondrial origin altered in Down syndrome
Samples Used: AG07095
Title: A small-molecule ICMT inhibitor delays senescence of Hutchinson-Gilford progeria syndrome cells
Samples Used: GM01972, AG03513, AG03258, and AG03512
Title: Fibroblasts from idiopathic Parkinson’s disease exhibit deficiency of lysosomal glucocerebrosidase activity associated with reduced levels of the trafficking receptor LIMP2
Samples Used: AG11743, AG06959, AG04061, AG13220, AG04355, AG11489, AG07141, AG05265, AG06010, AG06241, AG06281, AG20439, and AG20445
Title: Might Fibroblasts from Patients with Alzheimer’s Disease Reflect the Brain Pathology? A Focus on the Increased Phosphorylation of Amyloid Precursor Protein Tyr682 Residue
Title: Progerinin, an optimized progerin-lamin A binding inhibitor, ameliorates premature senescence phenotypes of Hutchinson-Gilford progeria syndrome
Samples Used: AG03198, AG11513, AG11498, AG03199, and AG00038
Title: Establishment human induced pluripotent stem cell line from idiopathic non-familial Parkinson’s disease patient using self-replicating RNA vector
Samples Used: AG20442
Title: Centrosome and ciliary abnormalities in fetal akinesia deformation sequence human fibroblasts
Samples Used: AG05965 and AG01972
Title: SAMMY-seq reveals early alteration of heterochromatin and deregulation of bivalent genes in Hutchinson-Gilford Progeria Syndrome
Samples Used: AG08498 and AG07095
Title: Exploring the potential of chitosan-based particles as delivery-carriers for promising antimicrobial glycolipid biosurfactants
Samples Used: AG22719
Title: Prolonged Glucocorticoid Exposure Does Not Accelerate Telomere Shortening in Cultured Human Fibroblasts
Samples Used: I90-83
Title: LSH mediates gene repression through macroH2A deposition
Samples Used: AG06814
Title: Large-Scale Topological Changes Restrain Malignant Progression in Colorectal Cancer
Samples Used: AG06814
Title: Oxidative cross-linking of fibronectin confers protease resistance and inhibits cellular migration
Samples Used: I90
Title: Modeling Human Cytomegalovirus-Induced Microcephaly in Human iPSC-Derived Brain Organoids
Samples Used: AG14048 and I90-10
Title: Lowered Cyclin E levels increase the efficiency and the specificity of capsaicin against
cancerous cells of mesothelium
Samples Used: AG07086
PDF available: here
Title: Generation of human control iPSC line CHOPi004-A from juvenile foreskin fibroblast cells
Samples Used: AG07095
Title: A method for differentiating human induced pluripotent stem cells toward functional cardiomyocytes in 96-well microplates
Samples Used: AG05836
Title: ESCRT-III controls nuclear envelope deformation induced by progerin
Samples Used: AG03512 and AG11513
Title: WRN modulates mRNA translation by influencing mRNA export from the nucleus through its interaction with the export receptor NXF1 in HeLa cancer cell
Samples Used: AG06814
Title: PAI-1-Dependent Inactivation of SMAD4-Modulated Junction and Adhesion Complex in Obese Endometrial Cancer
Samples Used: AG17870
Title: PICALM Rescues Endocytic Defects Caused by the Alzheimer’s Disease Risk Factor APOE4
Samples Used: AG07086
Title: Ascites-induced compression alters the peritoneal microenvironment and promotes metastatic success in ovarian cancer
Samples Used: AG07086
Title: Vulnerability of progeroid smooth muscle cells to biomechanical forces is mediated by MMP13
Samples Used: AG01972 and AG06917
Title: Nucleolar disruption, activation of P53 and premature senescence in POLR3A-mutated Wiedemann-Rautenstrauch syndrome fibroblasts
Samples Used: AG01972
Title: Lamin A‐mediated nuclear lamina integrity is required for proper ciliogenesis
Samples Used: AG01972, AG08466, AG11513, AG06297, AG06917, AG03512, and AG03257
Title: Biological Aging Modulates Cell Migration via Lamin A/C-Dependent Nuclear Motion
Samples Used: AG09558 and AG09602
Title: Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging
Samples Used: AG08434 and AG11725
Title: Novel resveratrol derivatives have diverse effects on the survival, proliferation and senescence of primary human fibroblasts
Samples Used: AG05965
Title: Apolipoprotein D-mediated preservation of lysosomal function promotes cell survival and delays motor impairment in Niemann-Pick type A disease
Samples Used: AG07323
Title: Lysosome Associated Protein Transmembrane 4B (LAPTM4B)-24 is the predominant protein isoform in human tissues and undergoes rapid, nutrient-regulated turnover
Samples Used: AG08498
Title: Cytoskeleton stiffness regulates cellular senescence and innate immune response in Hutchinson–Gilford Progeria Syndrome
Samples Used: AG03513, AG06917,AG08466, AG08468, AG08469, and AG08470
Title: Fully Phased Sequence of a Diploid Human Genome Determined de Novo from the DNA of a Single Individual
Samples Used: AG06814
Title: Generation of human induced pluripotent stem cell line from Alzheimer’s disease patient with PSEN2 N141I mutation using integration-free non-viral method
Samples Used: AG09908
Title: Reacquisition of a spindle cell shape does not lead to the restoration of a youthful state in senescent human skin fibroblasts
Samples Used: AG05397
Title: Reacquisition of a spindle cell shape does not lead to the restoration of a youthful state in senescent human skin fibroblasts
Samples Used: AG16086, AG06240, AG13152, AG13222, AG11572, AG06917, AG07493, and AG10677
Title: Reacquisition of a spindle cell shape does not lead to the restoration of a youthful state in senescent human skin fibroblasts
Samples Used: AG01523
Title: Repetitive elements as a transcriptomic marker of aging: Evidence in multiple datasets and models
Samples Used: AG09843 and AG11748
Title: Pathogenic variants in EP300 and ANKRD11 in patients with phenotypes overlapping Cornelia de Lange syndrome
Samples Used: AG09393 and AG14730
Title: Naked mole-rat very-high-molecular-mass hyaluronan exhibits superior cytoprotective properties
Samples Used: I90-78
Title: Restoration of lysosomal function after damage is accompanied by recycling of lysosomal membrane proteins
Samples Used: AG01518
Title: BCL-xL/BCL2L1 is a critical anti-apoptotic protein that promotes the survival of differentiating pancreatic cells from human pluripotent stem cells
Samples Used: AG16102
Title: Impaired Myofibroblast Dedifferentiation Contributes to Non-Resolving Fibrosis in Aging
Samples Used: I90-83 and I90-53
Title: Bioprospecting Sponge-Associated Marine Cyanobacteria to Produce Bioactive Compounds
Samples Used: AG01523
Title: Hydrogen Peroxide Mediates Artemisinin-Derived C-16 Carba-Dimer-Induced Toxicity of Human Cancer Cells
Samples Used: AG01522
Title: Unraveling LMNA Mutations in Metabolic Syndrome: Cellular Phenotype and Clinical Pitfalls
Samples Used: AG07095 and AG09309
Title: Human-Induced Neurons from Presenilin 1 Mutant Patients Model Aspects of Alzheimer's Disease Pathology
Samples Used: AG09429, AG02262, AG08711, AG08270, and AG08446
Title: Cancer cell-intrinsic function of CD177 in attenuating β-catenin signaling
Samples Used: AG11132
Title: Defective Mitochondrial Pyruvate Flux Affects Cell Bioenergetics in Alzheimer’s Disease-Related Models
Samples Used: AG09908, AG08525, AG08269, and AG09173
Title: Hyaluronidase-2 Regulates RhoA Signalling, Myofibroblast Contractility and other Key Pro-fibrotic Myofibroblast Functions
Samples Used: AG02262
Title: Persistent DNA damage triggers activation of the integrated stress response to promote cell survival under nutrient restriction
Samples Used: AG09319 and AG16409
Title: Activin A-Mediated Regulation of XT-I in Human Skin Fibroblasts
Samples Used: AG14284 and AG13145
Title: PRMT5 silencing selectively affects MTAP-deleted mesothelioma: In vitro evidence of a novel promising approach
Samples Used: AG07086
Title: Genetic correction of Werner syndrome gene reveals impaired pro-angiogenic function and HGF insufficiency in mesenchymal stem cells
Samples Used: AG00780
Title: Dysregulation of the retromer complex system in Down syndrome
Samples Used: AG04823 and AG08498
Title: Venereal Transmission of Vesicular Stomatitis Virus by Culicoides sonorensis Midges
Samples Used: AG08113
Title: Novel and prevalent non-East Asian ALDH2 variants; Implications for global susceptibility to aldehydes’ toxicity
Samples Used: AG07123
Title: A nuclear lamina‐chromatin‐Ran GTPase axis modulates nuclear import and DNA damage signaling
Samples Used: AG01972, AG11498, AG03199 and AG08469
Title: Predicting age from the transcriptome of human dermal fibroblasts
Samples Used: AG08498, AG13153, AG12207, AG13234, AG14251, AG12587, AG13144, AG16102, AG13967, AG16358, AG04386, AG13066, AG04457, AG04063, AG05413, AG16409, AG11745, AG04661, AG11698, AG05274, AG13244, AG06276, AG11484, AG11725, AG11162, AG11730, AG11556, AG11744, AG12954, AG12947, AG11154, AG04143, AG12989, AG09843, AG13962, AG11748, AG12493, AG13349, AG12602, AG04662, AG05247, AG05248, AG10884, AG11732, AG11017, AG11808, AG09975, AG13225, AG04065, AG11735, AG11357, AG06308, AG12597, AG13129, AG07124, AG12588, AG13208, AG09860, AG13065, AG06291, AG04461, AG12788, AG09559, AG07725, AG04054, AG12599, AG04064, AG07478, AG13018, AG09602, AG16086, AG08433, AG09599, AG04059 and AG09605
Title: ATM activation is impaired in human cells defective in RecQL4 helicase activity
Samples Used: AG17524
Title: Frenolicin B Targets Peroxiredoxin 1 and Glutaredoxin 3 to Trigger ROS/4E-BP1-Mediated Antitumor Effects
Samples Used: I91L-16 and AG06173
Title: A disease causing ATLASTIN 3 mutation affects multiple endoplasmic reticulum-related pathways
Samples Used: AG13334 and AG04151
Title: Autophagic cell death restricts chromosomal instability during replicative crisis
Samples Used: AG06814-N
Title: Fibrin-Targeted Polymerized Shell Microbubbles as Potential Theranostic Agents for Surgical Adhesions
Samples Used: AG07086
Title: REST and Neural Gene Network Dysregulation in iPSC Models of Alzheimer’s Disease
Samples Used: AG04455, AG08125, AG08379, AG08509, AG14244, AG09173, AG06869, AG07376, AG21158,
Title: Extranuclear DNA accumulates in aged cells and contributes to senescence and inflammation
Samples Used: AG04392, AG04433, AG04525, AG06555, AG02496, AG03058, AG04405, AG10578, AG11513,
Title: Chromosome alignment maintenance requires the MAP RECQL4, mutated in the Rothmund–Thomson
syndrome
Samples Used: AG05013 and AG18371
Title: Corticosteroids inhibit Mycobacterium tuberculosis-induced necrotic host cell death by abrogating
mitochondrial membrane permeability transition
Samples Used: AG05965
Title: Familial Alzheimer’s disease-linked presenilin mutants and intracellular Ca2+ handling: A single-organelle,
FRET-based analysis
Samples Used: AG09908, AG08525, AG06840 and AG08539
Title: Progerin accelerates atherosclerosis by inducing endoplasmic reticulum stress in vascular smooth muscle
cells
Samples Used: AG06297
Title: Analysis of somatic mutations identifies signs of selection during the in vitro aging of primary dermal
fibroblasts
Samples Used: AG13077, AG08433, AG10579 and AG07091
Title: A pleiotropic role for exosomes loaded with the amyloid β precursor protein carboxyl-terminal fragments in
in the brain of Down syndrome patients
Samples Used: AG06922 and AG07095
Title: mTOR hyperactivation in Down Syndrome underlies deficits in autophagy induction, autophagosome
formation, and mitophagy
Samples Used: AG06922, AG07095, AG07096 and AG04823
Title: Sp1 phosphorylation by ATM downregulates BER and promotes cell elimination in response to persistent
DNA damage
Samples Used: AG06173
Title: Everolimus rescues multiple cellular defects in laminopathy-patient fibroblasts
Samples Used: AG04110
Title: SCAMP4 enhances the senescent cell secretome
Samples Used: AG04110
Title: Meganuclease targeting of PCSK9 in macaque liver leads to stable reduction in serum cholesterol
Samples Used: AG07095
Title: Disease-associated short tandem repeats co-localize with chromatin domain boundaries
Samples Used: AG06103
Title: Landscape of the complete RNA chemical modifications in the human 80S ribosome
Samples Used: AG04645 and AG03738
Title: Replication stress shapes a protective chromatin environment across fragile genomic regions
Samples Used: I90-15
Title: Merkel cell polyomavirus infection of animal dermal fibroblasts
Samples Used: AG05308, AG05356, and AG06116
Title: LONGO: an R package for interactive gene length dependent analysis for neuronal identity
Samples Used: AG04148
Title: Increased MMP activity in curved geometries disrupts the endothelial cell glycocalyx creating a
proinflammatory environment
Samples Used: AG09799
