The NIMH Repository and Genomics Resource (NRGR) is the largest centralized national biorepository designed to advance psychiatric genetics research. The NRGR serves as the principal repository for the National Institute for Mental Health (NIMH) and provides researchers with access to high-quality biological materials—including DNA and cell lines, such as induced pluripotent stem cells (iPSCs). The resource contains over 3.8 million samples from more than 200,000 individuals with psychiatric illness and neurotypical controls. These biospecimens are paired with richly curated phenotypic, clinical, and genomic data to support large-scale, reproducible research.

The goal of the NRGR is to accelerate scientific understanding of the genetic and cellular bases of mental disorders and support translational neuroscience that will lead to new diagnostic tools, treatments, and preventive strategies for mental illnesses. Since its inception in 1989, the NRGR has distributed more than one million samples to more than 450 investigators worldwide and has supported approximately 1,800 genetic research studies on mental illness. 

Access to the NRGR is coming soon.