The NIGMS Human Genetic Cell Repository, sponsored by the National Institute of General Medical Sciences, provides scientists around the world with resources for cell and genetic research. Established in 1972 at the Coriell Institute for Medical Research, the NIGMS Repository contains more than 11,900 cell lines, primarily fibroblasts and transformed lymphoblasts, and more than 6,200 DNA samples. Currently, the NIGMS HGCR catalog also contains over 180 iPSC lines.
Repository samples represent a variety of disease states, chromosomal abnormalities, apparently healthy individuals, and many distinct human populations. These samples comprise over 1,100 different OMIM diagnoses, and have been referenced in over 8,100 scientific publications.
Data on this website and information derived from the samples in the NIGMS Repository may not be used to determine the identity of any individual who provided a sample. Sample data available in the NIGMS Repository regarding race and/or ethnicity is self-reported information provided by sample submitters. Please direct any questions about these policies to NIGMS@coriell.org.
Postdoctoral researcher Tatanya Pozner's latest paper, Human iPSC Reprogramming Success: The Impact of Approaches and Source Materials, was published this January.
read moreThe NIGMS Repository is now distributing 15 gene-edited induced pluripotent stem cell (iPSC) lines, supporting research into disease mechanisms and therapeutic development.
read moreTeam members from the NIGMS Repository traveled to Toronto this month to attend the American College of Medical Genetics and Genomics (ACMG) Annual Clinical Genetics Meeting.
read more
