Data collected on these subjects consisted of Control Clinical Data Elements as outlined in the Coriell NINDS Genetics Repository guidelines. These data elements were developed to be consistent with other NIH healthy control sample collections including that of the National Institute on Aging Late Onset Alzheimer's Disease Consortium (LOAD). These data include a detailed medical and family history.

None of the subjects on the panel have a history of neurological illness in themselves. All were asked specifically regarding the following disorders, which were not present: Alzheimer's, amyotrophic lateral sclerosis, ataxia, autism, bipolar disorder, cerebrovascular disease, dementia, dystonia, Parkinson's, and schizophrenia. None have any first degree relative with a known primary neurological disorder. Specifically none have a family history of any first degree relative with any of the following disorders: amyotrophic lateral sclerosis, ataxia, autism, cerebrovascular disease, dystonia, Parkinsons, schizophrenia.

All samples and data were collected with informed consent under local IRB approved protocols. These samples are generously shared by Drs. Eric Sorenson, Karen Furie, David Simon, Robert Brown, John Hardy, Petra Kaufmann, Dennis Dickson, Zbigniew Wszolek, Matthew Farrer, Catherine Lomen-Hoerth, Ray Watts, Kevin Boylan, Paul Gordon, Edward Kasarskis, Kapil Sethi, Daniel Newman, Russell Buono, Terry Scattergood, Zachary Simmons, Nickolas Margakis, Frederick Wooten, Andrew Siderowf, Tahseen Mozaffar, Ted Dawson, Rodger Elble, Robert Miller, William Young, Laura Sams, Merit Cudkowicz, and Peter Bosch.

Publications

Please cite the panel number and the NINDS Repository in any publications, and share those references the NINDS Repository Management Team at Coriell (NINDS@Coriell.org). Portions or all of this statement may be used in publications relevant to this panel.