Data collected on these subjects consisted of Control Clinical Data Elements as outlined in the Coriell NINDS Genetics Repository guidelines. These data elements were developed to be consistent with other NIH healthy control sample collections including that of the National Institute on Aging Late Onset Alzheimer's Disease Consortium (LOAD). These data include a detailed medical and family history.

None of the subjects on the panel have a history of neurological illness in themselves. All were asked specifically regarding the following disorders, which were not present: ALS, ataxia, autism, bipolar, brain aneurysm, dementia, dystonia, epilepsy, multiple sclerosis, Parkinson's, stroke, and schizophrenia. None have any first degree relative with any of these neurological disorders.

All samples and data were collected with informed consent under local IRB approved protocols. These samples are generously shared by Drs. John Hardy, Andrew Singleton, Karen Furie, Gregory Sorensen, Petra Kaufmann, Robert Brown Jr., David Simon, Catherine Lomen-Hoerth, Eric Sorenson, Kevin Boylan, Daniel Newman, Laura Sams, Kapil Sethi, Ray Watts, Alan Pestronk, Robert Miller, Nickolas Maragakis, William Young, and Paul Gordon.

Publications
Please cite the panel number and the NINDS Repository in any publications, and kindly share those references with the NINDS Repository Management Team at Coriell (NINDS@Coriell.org). Portions or all of this statement may be used in publications relevant to this panel.

Other Healthy Controls, Positive Controls
Control samples from individuals without neurological disease and with a range of clinical data are available via the NINDS Repository catalogue. Single samples from this panel can also be obtained, individually. Positive control samples for known causal genes are available, as listed, under specific disorders (see NINDS Repository catalog).