CH00066

CH00066 Neuronally-derived from Brain striatum

Description:

ST14A HTT-Q15, 1-548, HUMAN
HUNTINGTON DISEASE; HD

Affected:

No Data

Sex:

No Data

Age:

No Data

Overview

Repository

HD Community Biorepository

Biopsy Source

Brain striatum

Cell Type

Neuronally-derived

Tissue Type

Brain

Transformant

Large T antigen transformed

Sample Source

Neuronally-derived from Brain striatum

Family History

Species

Rattus norvegicus

Common Name

brown or Norway rat

Remarks

striatal cell line derived from rat embryonic day 14 (E14) expressing a Huntingtin fragment (1-548) containing 15 polyglutamine repeats CELLS SHIPPED FROZEN

Phenotypic Data

Remarks

striatal cell line derived from rat embryonic day 14 (E14) expressing a Huntingtin fragment (1-548) containing 15 polyglutamine repeats CELLS SHIPPED FROZEN

Publications

Cattaneo E, Conti L, Generation and characterization of embryonic striatal conditionally immortalized ST14A cells Journal of neuroscience research53:223-34 1998

PubMed ID: 9671979

External Links

Gene Cards

HD (verified)

Gene Ontology

GO:0003714 transcription corepressor activity

GO:0005215 transporter activity

GO:0005515 protein binding

GO:0005625 soluble fraction

GO:0005634 nucleus

GO:0005737 cytoplasm

GO:0006915 apoptosis

GO:0006917 induction of apoptosis

GO:0007610 behavior

GO:0008017 microtubule binding

GO:0009405 pathogenesis

GO:0009887 organogenesis

NCBI Gene

Gene ID:3064

NCBI GTR

143100 HUNTINGTON DISEASE; HD

OMIM

143100 HUNTINGTON DISEASE; HD

Culture Protocols

striatal cell line derived from rat embryonic day 14 (E14) expressing a Huntingtin fragment (1-548) containing 15 polyglutamine repeats CELLS SHIPPED FROZEN

Split Ratio

1:3

Temperature

33 C

Percent CO2

Percent O2

AMBIENT

Medium

Dulbecco Modified Eagles Medium (high glucose) with 2mM L-glutamine or equivalent

Serum

10% fetal bovine serum Not inactivated

Remarks

striatal cell line derived from rat embryonic day 14 (E14) expressing a Huntingtin fragment (1-548) containing 15 polyglutamine repeats CELLS SHIPPED FROZEN

PDF

CH00066 Cell Culturing Protocols

Supplement

Pricing

Commercial:

$100.00USD

Academic &
Non-profit:

$100.00USD

Description:

ST14A HTT-Q15, 1-548, HUMAN HUNTINGTON DISEASE; HD

Affected:

No Data

Sex:

No Data

Age:

No Data

Overview

Phenotypic Data

Publications

External Links

Culture Protocols

ST14A HTT-Q15, 1-548, HUMAN
HUNTINGTON DISEASE; HD