AG20441
LCL from B-Lymphocyte
Description:
PARKINSON DISEASE
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Repository
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NIA Aging Cell Culture Repository
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| Subcollection |
Heritable Diseases |
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Biopsy Source
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Peripheral vein
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Cell Type
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B-Lymphocyte
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Tissue Type
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Blood
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Transformant
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Epstein-Barr Virus
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Sample Source
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LCL from B-Lymphocyte
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Race
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White
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Family Member
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1
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Relation to Proband
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proband
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Confirmation
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Clinical summary/Case history
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ISCN
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45,X[2]/46,XY[48]
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Species
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Homo sapiens
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Common Name
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Human
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Remarks
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| IDENTIFICATION OF SPECIES OF ORIGIN |
Species of Origin confirmed by LINE assay |
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| Remarks |
Clinically affected; onset at age 51 with stiff neck which began to involve his right side; mild intermittent resting tremor; rigidity on right side with relatively good movement on left side of body; cog-wheel rigidity; akinesia; seborrhea; akathisia; deep tendon reflexes are hypoactive, but symmetric; bilateral flexor plantar responses; treated and improved with Sinemet; when not taking medication, he has more rightside stiffness and akathisia; negative family history; culture grows slowly; see AG20442 Fibroblast |
| Split Ratio |
1:3 |
| Temperature |
37 C |
| Percent CO2 |
5% |
| Medium |
Roswell Park Memorial Institute Medium 1640 with 2mM L-glutamine or equivalent |
| Serum |
15% fetal bovine serum Not Inactivated |
| Substrate |
None specified |
| Subcultivation Method |
dilution - add fresh medium |
| Supplement |
- |
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