HLA58
96 WELL PLATE OF DNA SAMPLES
Description:
HLA REFERENCE PANEL - PANEL OF 58 DNA SAMPLES
Aliquot Size:
10 µg each
Brief Description:
Selected based on their relevance for testing of the human leukocyte antigen (HLA) loci, the highly-characterized DNA samples in this panel have each been extracted from 58 ethnically diverse cell lines from the NIGMS Human Genetic Cell Repository. These samples were characterized in a collaborative effort involving the CDC Genetic Testing Reference Materials Coordination Program (Get-RM), 3 clinical laboratories, and the NIGMS Repository. Click here to view the sample data generated by the multiple laboratories involved in this project.
The plate contains 10 µg DNA in 50 µl from each of 58 individual cell lines, normalized to a concentration of 200 µg/ml. Click here  to view the sample plate locations.
Reference Publication (also located on the publications tab for this product):
Characterization of 108 Genomic DNA Reference Materials for 11 Human Leukocyte Antigen Loci: A GeT-RM Collaborative Project. J Mol Diagn. 2018 Sep;20(5):703-715. (Pubmed ID: 29959025).
| Bettinotti MP1, Ferriola D2, Duke JL2, Mosbruger TL2, Tairis N2, Jennings L3, Kalman LV4, Monos D5., Characterization of 108 Genomic DNA Reference Materials for 11 Human Leukocyte Antigen Loci: A GeT-RM Collaborative Project. Journal of Molecular Diagnostics18:30111-30119 2018 |
| PubMed ID: 29959025 |
| Catalog ID | Sex | Age at Sampling | Family | Relationship | Gene | Mutation | Race |
| NA17201 | Male | 25 YR | 700 | | CYP2C19 | 21158G>A (Mono) | |
| NA09301 | Male | 50 YR | 2146 | father | | | White |
| NA12244 | Female | | 1416 | daughter | CYP2D6 | ARG296CYS AND SER486THR (Mono), VAL11MET,ARG296CYS,SER486THR (Mono) | White |
| NA10005 | Female | 37 YR | 1154 | mother | CYP2D6 | THR107ILE, ARG296CYS, AND SER486THR (Mono), VAL136MET,ARG296CYS,VAL338MET,SER486THR (Mono) | Black/African American |
| NA07439 | Female | | 1047 | mother | CYP2C19 | PRO227LEU (Mono) | Black/African American |
| NA16688 | Female | 75 YR | | proband | | | Chinese |
| NA17286 | Female | 73 YR | | | CYP2D6 | IVSDS3, G>A, +1 (Mono) | |
| NA17289 | Female | 73 YR | | | CYP2D6 | IVSDS3, G>A, +1 (Mono) | |
| NA23093 | Female | 70 YR | | proband | HLA-B | HLA-B*1502 (Mono) | Asian |
| NA17247 | Female | 65 YR | | | HLA-B | HLA-B*5701 (Mono) | |
| NA17290 | Female | 5 YR | | | HLA-B | HLA-B*5701 (Mono) | |
| NA17129 | Female | 48 YR | | | UGT1A1 | 5 TA Repeats (Mono), 6 TA Repeats (Mono) | |
| NA17246 | Female | 46 YR | | | CYP2C19, CYP2D6 | IVSDS3, G>A, +1 (Mono), TRP120ARG (Mono) | |
| NA17230 | Female | 37 YR | | | CYP2D6 | IVSDS3, G>A, +1 (Mono) | |
| NA17440 | Female | 35 YR | | proband | | | Hispanic/Latino |
| NA17267 | Female | 34 YR | | | CYP2D6 | IVSDS3, G>A, +1 (Mono) | |
| NA17229 | Female | 33 YR | | | | | |
| NA17234 | Female | 31 YR | | | | | |
| NA17119 | Female | 29 YR | | | UGT1A1 | 6 TA Repeats (Mono), 8 TA Repeats (Mono) | |
| NA17261 | Female | 28 YR | | | CYP2D6 | IVSDS3, G>A, +1 (Mono) | |
| NA17084 | Female | 26 YR | | | | | |
| NA17213 | Female | 26 YR | | | | | |
| NA17130 | Female | 24 YR | | | UGT1A1 | 6 TA Repeats (Mono), 8 TA Repeats (Mono) | |
| NA17256 | Female | 24 YR | | | | | |
| NA17296 | Female | 24 YR | | | CYP2D6 | 2613_2615delAGA (Mono) | |
| NA17204 | Female | 23 YR | | | | | |
| NA17206 | Female | 23 YR | | | CYP2D6 | IVSDS3, G>A, +1 (Mono) | |
| NA17039 | Female | 22 YR | | | | | |
| NA17210 | Female | 22 YR | | | CYP2D6 | IVSDS3, G>A, +1 (Mono) | |
| NA17274 | Female | 19 YR | | | CYP2D6 | ARG296CYS AND SER486THR (Mono) | |
| NA17019 | Female | | | | HLA-B | HLA-B*1502 (Mono), HLA-B*1511 (Mono) | |
| NA17057 | Female | | | | CYP2D6, UGT1A1 | 6 TA Repeats (Bi), PRO34SER (Mono) | |
| NA17058 | Female | | | | UGT1A1 | 6 TA Repeats (Mono), 7 TA Repeats (Mono) | |
| NA17228 | Male | 75 YR | | | | | |
| NA16689 | Male | 74 YR | | proband | | | Chinese |
| NA17285 | Male | 69 YR | | | | | |
| NA17222 | Male | 68 YR | | | | | |
| NA17211 | Male | 65 YR | | | CYP2D6 | IVSDS3, G>A, +1 (Mono) | |
| NA17237 | Male | 63 YR | | | CYP2D6 | IVSDS3, G>A, +1 (Mono) | |
| NA17240 | Male | 60 YR | | | CYP2D6, HLA-B | HLA-B*5701 (Mono), PRO34SER (Mono) | |
| NA17269 | Male | 55 YR | | | | | |
| NA17212 | Male | 51 YR | | | | | |
| NA17078 | Male | 43 YR | | | HLA-B | HLA-B*5703 (Mono) | |
| NA17466 | Male | 38 YR | | proband | | | Hispanic/Latino |
| NA17226 | Male | 36 YR | | | CYP2D6 | IVSDS3, G>A, +1 (Mono) | |
| NA17214 | Male | 33 YR | | | | | |
| NA17219 | Male | 33 YR | | | | | |
| NA17115 | Male | 31 YR | | | HLA-B, UGT1A1 | 7 TA Repeats (Bi), HLA-B*5703 (Mono) | |
| NA17295 | Male | 31 YR | | | CYP2D6 | IVSDS3, G>A, +1 (Mono) | |
| NA17282 | Male | 30 YR | | | | | |
| NA23090 | Male | 29 YR | | proband | HLA-B | HLA-B*1502 (Mono), HLA-B*5101 (Mono) | |
| NA17203 | Male | 27 YR | | | CYP2D6 | IVSDS3, G>A, +1 (Mono) | |
| NA17232 | Male | 27 YR | | | | | |
| NA17205 | Male | 26 YR | | | | | |
| NA17264 | Male | 25 YR | | | CYP2D6 | IVSDS3, G>A, +1 (Mono) | |
| NA17618 | Male | 21 YR | | proband | | | Hispanic/Latino |
| NA17114 | Male | 20 YR | | | UGT1A1 | 6 TA Repeats (Mono), 7 TA Repeats (Mono) | |
| NA17020 | Male | | | | | | |
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