| Remarks |
Clinically affected; hemoglobin E/beta-thalassemia major; started requiring transfusions about age 9 years; more than 150 transfusions over lifetime; iron overload controlled with chelation therapy; splenectomy; hemoglobin electrophoresis results: HbA = 84.7%, HbA2 = 13.5%, HbF = 1.8%, HbS = 0%, 13.5% Hb E/comigrates with HbA2; hemoglobin = 10.6 g/dl; MCV = 84.2.
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