Description:
BURKITT LYMPHOMA; BL
|
Repository
|
NIGMS Human Genetic Cell Repository
|
| Subcollection |
Heritable Diseases
dbGaP |
| Class |
Heritable Cancer Syndromes and other Cancers |
| Quantity |
25 µg |
| Quantitation Method |
Please see our FAQ |
|
Biopsy Source
|
Peripheral vein
|
|
Cell Type
|
B-Lymphocyte
|
|
Tissue Type
|
Blood
|
|
Transformant
|
Epstein-Barr Virus
|
|
Sample Source
|
DNA from LCL
|
|
Race
|
Black/African American
|
|
Ethnicity
|
YORUBA
|
|
Relation to Proband
|
proband
|
|
Confirmation
|
Clinical summary/Case history
|
|
Species
|
Homo sapiens
|
|
Common Name
|
Human
|
|
Remarks
|
|
| IDENTIFICATION OF SPECIES OF ORIGIN |
Species of Origin Confirmed by Chromosome Analysis |
| |
| Remarks |
RAJI; ATCC CCL 86; G6PD type B; negative for Epstein Barr virus; negative for reverse transcriptase; 46,XY, 4q+, 9p+, 14q+; 46% of cells show random chromosome loss or gain |
| Lattier DL, States JC, Hutton JJ, Wiginton DA, Cell type-specific transcriptional regulation of the human adenosine deaminase gene. Nucleic Acids Res17:1061-76 1989 |
| PubMed ID: 2784203 |
| |
| Dasgupta MK, Kovithavongs T, Schlaut J, Longenecker BM, Dossetor JB, Antibody-mediated cellular cytotoxicity against Raji cells ADCC(Raji): evaluation of false positives in the detection of circulating immune complexes by Raji-cell assay. J Clin Immunol2:197-204 1982 |
| PubMed ID: 6749886 |
| |
| Imai K, Galloway DR, Ferrone S, Serological and immunochemical analysis of the specificity of xenoantiserum 8986 elicited with hybrids between human melanoma cells and murine fibroblasts. Cancer Res41:1028-33 1981 |
| PubMed ID: 6161692 |
| |
| Carrel S, Gross N, Salvi S, Rabbit antiserum against Daudi-cell membrane fractions detects cell surface antigens present on subpopulations of human lymphocytes. J Immunol120:1587-93 1978 |
| PubMed ID: 307019 |
| |
| Swallow DM, Gardiner SE, Harris H, Arthur E, Steel CM, Evans HJ, Lysosomal enzymes in human lymphoblastoid lines: unusual characteristics of RAJI and DAUDI. Ann Hum Genet41:9-16 1977 |
| PubMed ID: 200169 |
| |
| Epstein MA, Achong BG, Barr YM, Zajac B, Henle G, Henle W, Morphological and virological investigations on cultured Burkitt tumor lymphoblasts (strain Raji). J Natl Cancer Inst37:547-559 1966 |
| PubMed ID: 4288580 |
|
|