AG06939
Fibroblast from Skin, Arm
Description:
PAN TROGLODYTES
ORDER: PRIMATES
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Repository
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NIA Aging Cell Culture Repository
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| Subcollection |
Nonhuman Primates
Animals |
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Biopsy Source
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Arm
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Cell Type
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Fibroblast
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Tissue Type
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Skin
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Transformant
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Untransformed
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Sample Source
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Fibroblast from Skin, Arm
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Family Member
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1
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Relation to Proband
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proband
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Confirmation
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Clinical summary/Case history
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Species
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Pan troglodytes
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Common Name
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chimpanzee
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Remarks
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| Remarks |
The skin biopsy was taken ante-mortem on 7/25/83 from the medial surface of the left arm. |
| Babcock M, Yatsenko S, Stankiewicz P, Lupski JR, Morrow BE, AT-rich repeats associated with chromosome 22q112 rearrangement disorders shape human genome architecture on Yq12 Genome research17:451-60 2007 |
| PubMed ID: 17284672 |
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| Han K, Sen SK, Wang J, Callinan PA, Lee J, Cordaux R, Liang P, Batzer MA, Genomic rearrangements by LINE-1 insertion-mediated deletion in the human and chimpanzee lineages. Nucleic Acids Res33(13):4040-52 2005 |
| PubMed ID: 16034026 |
| |
| Ho HJ, Ray DA, Salem AH, Myers JS, Batzer MA, Straightening out the LINEs: LINE-1 orthologous loci. Genomics85(2):201-7 2005 |
| PubMed ID: 15676278 |
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| Fortna A, Kim Y, MacLaren E, Marshall K, Hahn G, Meltesen L, Brenton M, Hink R, Burgers S, Hernandez-Boussard T, Karimpour-Fard A, Glueck D, McGavran L, Berry R, Pollack J, Sikela JM, Lineage-specific gene duplication and loss in human and great ape evolution. PLoS Biol2(7):E207 2004 |
| PubMed ID: 15252450 |
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| Otieno AC, Carter AB, Hedges DJ, Walker JA, Ray DA, Garber RK, Anders BA, Stoilova N, Laborde ME, Fowlkes JD, Huang CH, Perodeau B, Batzer MA, Analysis of the human Alu Ya-lineage. J Mol Biol342(1):109-18 2004 |
| PubMed ID: 15313610 |
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| Morrish TA, Gilbert N, Myers JS, Vincent BJ, Stamato TD, Taccioli GE, Batzer MA,
Moran JV, DNA repair mediated by endonuclease-independent LINE-1 retrotransposition. Nat Genet31(2):159-65 2002 |
| PubMed ID: 12006980 |
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| Conte RA,Samonte RV,Verma R, Localization of subtelomeric sequences of human chromosomes 1q, 11p, 13q, and 16q in the higher primates. Genetica105:31-4 1999 |
| PubMed ID: 10483091 |
| |
| Conte RA,Samonte RV,Verma R, Evolutionary divergence of the oncogenes GLI, HST and INT2. Heredity81 ( Pt 1):10-3 1998 |
| PubMed ID: 9720300 |
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| Tarzami ST,Kringstein AM,Conte RA,Verma R, Unique genomic sequences in human chromosome 16p are conserved in the great apes. Mol Gen Genet253:512-4 1997 |
| PubMed ID: 9037113 |
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| Janczewski DN, Goldman D, O'Brien SJ, Molecular genetic divergence of orang utan (Pongo pygmaeus) subspecies based on isozyme and two-dimensional gel electrophoresis. J Hered81:375-87 1990 |
| PubMed ID: 2230076 |
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| Ledbetter DH, Ledbetter SA, Nussbaum RL, Implications of fragile X expression in normal males for the nature of the mutation. Nature324:161-3 1986 |
| PubMed ID: 3785381 |
| Cumulative PDL at Freeze |
12 |
| Passage Frozen |
7 |
| Split Ratio |
1:3 |
| Temperature |
37 C |
| Percent CO2 |
5% |
| Medium |
MEM (Eagle) Alpha Modification with nucleosides with 2mM L-glutamine or equivalent |
| Serum |
10% fetal bovine serum Not inactivated |
| Substrate |
None specified |
| Subcultivation Method |
trypsin-EDTA |
| Supplement |
- |
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